• 17β-estradiol modulates NGF and BDNF expression through ERβ mediated ERK signaling in cortical astrocytes 

  Langhnoja, J M; L. K, Buch; Pillai, P P (Biologia volume, 2018-08)

  17β-estradiol is known to exert neurotrophic and neuroprotective effects through classical estrogen receptors [ERs], ERα and ERβ, on a variety of cell types either by genomic or non-genomic actions. The actions of estradiol ...
• Role of astrocytic MeCP2 in regulation of CNS myelination by affecting oligodendrocyte and neuronal physiology and axo–glial interactions 

  Lipi, B; Jaldeep, L; Prakash, P (Experimental brain research, 2018-08)

  Astrocytes perform several critical functions such as promoting neuronal maturation, neuronal survival, maintaining and supporting neurons and oligodendrocytes. Astrocytes participate in the formation of nodes of Ranvier. ...
• The effect of different chemical treatments and salt stresson the germination potential of tavernieracuneifolia (roth) ali seeds 

  P, Mangalorkar; Rana, K; Parikh, Rahul; Nagar, p (Journal of Chemical, Biological and Physical Sciences, 2014-01)

  Tavernieracuneifoliais an ethnobotanically important traditional medicinal plant of Semi-Arid region of India belonging to the family of Fabaceae. As the plant is ecologically identified as glycophyte the seeds were treated ...
• Design, Synthesis, In Silico Studies and In Vitro Anticancer Activity of 3-(4-Methoxyphenyl)azetidine Derivatives 

  Parmar, D. R.; Rayani, R. H.; Vala, A. G.; Kusurkar, R.V.; Manvar, R.K.; Talukdar, S.N.; Preeti; Zunjar, V.; Battula, S.; Soni, J Y. (Chemistry Select, 2020-12)

  A series of 3‐(4‐methoxyphenyl)azetidine analogues were synthesized and screened for their in vitro anticancer activity against nine different human cancer cell lines using the cell counting kit‐8 (CCK‐8) assay. The ...
• Recapitulating bone development through engineered mesenchymal condensations and mechanical cues for tissue regeneration 

  McDermott, Anna M.; Herberg, Samuel; Mason, Devon E.; Collins, Joseph M.; Pearson, Hope B.; Dawahare, James H.; Tang, Rui; Patwa, Amit N.; Grinstaff, Mark W.; Kelly, Daniel J.; Alsberg, Eben; Boerckel, Joel D. (SCIENCE TRANSLATIONAL MEDICINE, 2019-06)

  Large bone defects cannot form a callus and exhibit high complication rates even with the best treatment strategies available. Tissue engineering approaches often use scaffolds designed to match the properties of mature ...
• Intron specific polymorphic site of vaspin gene along with vaspin circulatory levels can influence pathophysiology of type 2 diabetes 

  Rathva, Nirali; Patel, Roma; Palil, Sayantani Pramanik; Parmar, Nishant; Ramchandran, A.V.; Begum, Rasheedunnisa (National Center for Biotechnology infomation, 2020-02)

  Vaspin, an insulin-sensitizing adipokine, has been associated with type 2 diabetes (T2D). The present study aimed to investigate the distribution of genotypes and high-risk alleles of vaspin genetic variants (rs77060950 ...
• β-cell replenishment: Possible curative approaches for diabetes mellitus 

  Rathva, Nirali; Patel, Roma; Palil, Sayantani Pramanik; Parmar, Nishant; Rana, Sneha; Ansari, Mohammad Isamil; Ramchandran, A.V.; Begum, Rasheedunnisa (Nutrition, Metabolism and Cardiovascular Diseases, 2020-10)

  Aims Diabetes mellitus (DM) is a disorder of heterogeneous etiology marked by persistent hyperglycemia. Exogenous insulin is the only treatment for type 1 diabetes (T1D). Islet transplantation is a potential long cure for ...
• Antioxidant activities and phenolics profiling of different parts of Carica papaya by LCMS-MS 

  zunjar, Vishwanath; Mammen, D; Trivedi, Bhavna (Natural Product Research, 2015)

  This article deals with the comparison of the antioxidant activity of aqueous extracts of various parts of Carica papaya L. The evaluation of total phenolic content and total flavonoid content revealed high antioxidant ...
• Antithrombocytopenic activity of carpaine and alkaloidal extract of carica papaya linn. Leaves in busulfan induced thrombocytopenic wistar rats 

  zunjar, Vishwanath; Das, Ranjit Prasad; Jivrajani, Mehul; Trivedi, Bhavna; Nivsarkar, Manish (National Library of Medicine, 2016-04)

  Ethnopharmacological relavance: The decoction of Carica papaya Linn. leaves is used in folklore medicine in certain parts of Malaysia and Indonesia for the treatment of different types of thrombocytopenia associated with ...
• Rapid, effective deprotection of tert-butoxycarbonyl (boc) amino acids and peptides at high temperatures using a thermally stable ionic liquid 

  Bhawal, Sumit S; Patil, Rahul A; Armostrong, Dainiel W (Electronic Supplementary Material (ESI) for RSC Advances, 2015-10)

  A method for high temperature Boc deprotection of amino acids and peptides in a phosphonium ionic liquid is described. The ionic liquid had low viscosity, high thermal stability and demonstrated a beneficial effect. The ...
• Improving cytotoxicity by changing a linker from diphenylether to diphenylmethane and now to phenylene in binuclear dithiocarbamate complexes: synthesis and cytotoxicity study 

  Sing, Vinay K; Pillai, Vineeta; Patel, Shailyakumari K; Buch, Lipi (European Chemical societies publishing, 2019-08)

  α-chloroamide 1,3-bis(2-chloroacetamido)phenylene (L’) is selected as a lead compound to derive 1,3-bis(2-(alkylamino)acetamido)phenylene (L1-L3). A programmed self-assembly involving L1-L3, CS2 and NiII, CuII or ZnII ions ...
• New binuclear dithiocarbamate complexes [M2-µ2-bis-{(κ2S,S-S2CN(R)CH2CONHC6H4)2CH2}] (M=NiII, CuII, and ZnII): synthesis, characterization, DFT, and in vitro cytotoxic study 

  Sing, Vinay K; Pillai, Vineeta; Gohil, Prakash; Patel, Shailyakumari K; Buch, Lipi (Taylor & Francis, 2018-05)

  A new series of binuclear dithiocarbamate macrocyclic complexes [M2-µ2-bis-{(κ2S,S-S2CN(R)CH2CONHC6H4)2CH2}] {R=Cy, M = NiII 1a, CuII 1b, ZnII 1c; R=iPr, M = NiII 2a, CuII 2b, ZnII 2c; R=nBu, M = NiII 3a, CuII 3b, ZnII 3c} ...
• Binuclear diphenyltin(IV)dithiocarbamate complexes bearing functionalized linkers: Synthesis, spectral characterization, DFT and in vitro anticancer activity 

  Pillai, Vineeta; Patel, Shailykumari K.; Buch, Lipi; Sing, Vinay K (Applied Organometallic Chemistry, 2018-10)

  A new series of diphenyltin(IV)dithiocarbamate complexes of the type [(Ph2Sn)2-μ2-bis{(κ2S,S-S2CN(R)CH2CONHC6H4)2SO2}] {R = Cy (1), iPr (2), nBu (3)} and [(Ph2Sn)2-μ2-bis{(κ2S,S-S2CN(R)CH2CONH)2C6H4}] {R = Cy (4), iPr (5)} ...
• Derivatives of dapsone (dap): synthesis and study on in vitro anticancer activity and dna laddering against hep g2 and c6 human cancer cell lines 

  Pillai, Vineeta; Kadu, Rahul; Buch, Lipi; Singh, Vinay K. (Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, 2017-05)

  Interesting biological profile of dapsone (dap) has encouraged us to derivatize it further into a novel series of diamines 4,4’-bis (2-(alkylamino) acetamido) diphenylsulfone L1 -L3 and their ensuing metallomacrocyclic ...
• Functional characterization of dosage-dependent lethal mutation of ubiquitin in saccharomyces cerevisiae 

  Doshi, Ankita; Mishara, Pradeep; Sharma, Mrinal; Prabha, C. Ratna (FEMS yeast research, 2014-11)

  Ubiquitin is a eukaryotic protein with 96% sequence conservation from yeast to human. Ubiquitin plays a central role in protein homeostasis and regulation of protein function. We have reported on the generation of variants ...
• Structural changes induced by L50P and I61T single mutations of ubiquitin affect cell cycle progression while impairing its regulatory and degradative functions in Saccharomyces cerevisiae 

  Doshi, Ankita; sharma, Mrinal; Prabha, C. Ratna (International Journal of Biological Macromolecules, 2017-06)

  Posttranslational conjugation of ubiquitin to proteins either regulates their function directly or concentration through ubiquitination dependent degradation. High degree of conservation of ubiquitin's sequence implies ...
• Study of mesomorphism through a novel homologous series and its relation to molecular structure 

  Dodhi, A.A.; Chauhan, B.C. (Taylor & Francis, 2015-01)

  A novel homologous series 4-(4′-n-alkoxy benzoyloxy)-3-chloro phenyl azo,3″,4″-dichlorobenzenes was synthesized with a view to understand and establish the relation between mesomorphism and the molecular structure. The ...
• Dependence of molecular structure on mesomorphic behavior with special reference to central bridge 

  Patel, Brijesh; Doshi, Ankita A; Doshi, A.V. (Taylor & Francis, 2015-03)

  A novel homologous series of liquid crystalline 4-(4′-n-alkoxy cinnamoyloxy)-4″-methoxy benzyl cinnamates was synthesized and studied with a view to understand and establish the effects of molecular structure on liquid ...
• In-vivo uptake of fluoride by pearl millet [pennisetum typhoideum rich.] Irrigated with fluorinated groundwater 

  Parikh, Punita; Parikh, Rahul (International Journal of Allied Practice, Research and Review, 2015)

  In Kheralu taluka of mehsana district, people have health risk due to the excess of fluoride in the drinking water and dietary materials. Irrigation of agricultural lands with high fluoride content has lead to rise in ...
• Synthesis of thermally stable geminal dicationic ionic liquids and related ionic compounds: an examination of physicochemical properties by structural modification 

  Patil, Rahul A.; Talebi, Mohsen; Xu, Chengdong; Bhawal, Sumit S.; Armstrong, Daniel W. (Chemistry of Materials, 2016)

  Geminal dicationic ionic liquids (ILs) often display higher thermal stabilities, viscosities, and densities compared to traditional monocationic ILs. Also, dicationic ILs have advantages in terms of tuning of their ...

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