Acute exposure of pyrazosulfuron ethyl induced haematological and blood Biochemical changes in the freshwater teleost fish oreochromis mossambicus

Abstract

Buildup of agriculture pesticides in the aquatic habitat through natural run-off is a major problem faced by developing and developed countries. The present study was designed to evaluate the 96 hr LC50 of herbicide, Pyrazosulfuron-Ethyl which belongs to Sulfonylurea group. Using static bioassay with continuous aeration under laboratory conditions, acute toxicity of the herbicide was determined for fresh water fish Oreochromis mossambicus. Hematological and biochemical parameters are used as health indicators to detect the functional status of fish under acute exposure. Hence, biochemical parameters like plasma glucose, protein, albumin and globulin were also studied to evaluate the toxic potential of the herbicide. The herbicide led to significant changes in the hematological parameters such as RBC count, Hb, PCV, MCH, MCHC, MCV and WBC count and biochemical parameters. These alterations can be used as non specific biomarkers in herbicide contaminated aquatic ecosystem.