Quantum dot lipid oligonucleotide bioconjugates: toward a new anti-microrna nanoplatform

Barthélémy, Philippe; Beztsinna, Nataliia; Aimé, Ahissan; Bestel, Isabelle; Pokolenko, Alexander; Patwa, Amit

NUV Institutional Digital Repository Home
→
Academic Publications
→
Scholarly Publications
→
Education and Liberal Arts
→
Journal Papers
→
View Item

dc.contributor.author	Aimé, Ahissan
dc.contributor.author	Beztsinna, Nataliia
dc.contributor.author	Patwa, Amit
dc.contributor.author	Pokolenko, Alexander
dc.contributor.author	Bestel, Isabelle
dc.contributor.author	Barthélémy, Philippe
dc.date.accessioned	2019-06-14T05:00:52Z
dc.date.available	2019-06-14T05:00:52Z
dc.date.issued	2013-07-26
dc.identifier.issn	1043-1802 (P-ISSN)
dc.identifier.issn	1520-4812 (E-ISSN)
dc.identifier.uri	http://27.109.7.66:8080/xmlui/handle/123456789/580
dc.description	Bioconjugate Chemistry, Vol-24, Issue-8, 2013, p. 1345-1355	en_US
dc.description.abstract	The construction of new nanotools is presented here using the example of fluorescent semiconductor nanocrystals, quantum dots (QDs). In this study, the implementation of the new lipid oligonucleotide conjugate-functionalized quantum dots (LON-QDs) is realized in four steps: (i) the synthesis of the lipid oligonucleotide conjugates (LONs), (ii) the encapsulation of QDs by nucleolipids and LONs, (iii) the study of the duplex formation of LON-QDs with the complementary ON partners, and (iv) the cellular uptake of the LON-QD platform and hybridization with the target ONs (microRNA and miR-21).	en_US
dc.language.iso	en_US	en_US
dc.publisher	American Chemical Society	en_US
dc.subject	Quantum dots	en_US
dc.subject	Bioconjugates	en_US
dc.subject	Lipid-oligonucleotide	en_US
dc.subject	Self-assembly	en_US
dc.subject	Surface plasmon resonance	en_US
dc.title	Quantum dot lipid oligonucleotide bioconjugates: toward a new anti-microrna nanoplatform	en_US
dc.type	Article	en_US