dc.contributor.author |
Pandya, Parth |
|
dc.contributor.author |
Parikh, Pragna |
|
dc.date.accessioned |
2021-08-02T10:19:33Z |
|
dc.date.available |
2021-08-02T10:19:33Z |
|
dc.date.issued |
2016-06 |
|
dc.identifier.issn |
2320-5407 |
|
dc.identifier.uri |
http://27.109.7.66:8080/xmlui/handle/123456789/668 |
|
dc.description |
International Journal of Advanced Research (2016), Volume 4, Issue 6, 830-840 |
en_US |
dc.description.abstract |
The effect of agrochemicals in general and pesticides in particular on nontarget organisms has been a source of worldwide attention and concern for
decades. Pesticide residues in water are a major concern as they pose a
serious threat to biological communities including humans. The present study
deals with the sub-lethal effect of four agrochemicals namely insecticide
(Imidaclorprid-IMI), Herbicide (Pyraonsulfuron Ethyl-PE), Fungicide
(Curzate-CZ) and plant nutrient (Mixture of Trace metal ions-MN) on the
alteration in gene expression pattern of various target genes of hypothalamus
pituitary gonadal axis (HPG) in Oreochromis mossambicus. IMI exposure
resulted in an up regulation of the kisspeptin 2 and GnRH-I mRNA level in
hypothalamic region, gonadotropin receptors (GtH-Ir and IIr) and estrogen
receptor (ERI) in ovary. PE and CZ exposure altered the GtHIIr and Estrogen
receptor II (ERII) mRNA levels in brain and ovary. Micronutrient mixture
(MN) exposure altered the kiss 2 and ER-I transcript in hypothalamic region
of brain and GtH-IIr and ER-I receptor in ovary. The result of the present
study implies that agrochemicals has modified HPG axis which ultimately
lead to the reduced reproductive fecundity of the fish. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
International Journal of Advanced Research |
en_US |
dc.subject |
HPG axis |
en_US |
dc.subject |
Adverse Effects |
en_US |
dc.subject |
Fish |
en_US |
dc.subject |
Agrochemicals |
en_US |
dc.title |
Agrochemicals induced gene expression alterations in O. mossambicus |
en_US |
dc.type |
Article |
en_US |